Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FATTY ACID OXIDATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
FATTY_ACID_OXIDATION["FATTY ACID OXIDATION"]
FATTY_ACID_OXIDATION -->|"involved_in"| Tumor_Cell_Energy_Metabolism["Tumor Cell Energy Metabolism"]
FATTY_ACID_OXIDATION -->|"implicated in"| MITOCHONDRIA["MITOCHONDRIA"]
FATTY_ACID_OXIDATION -->|"implicated in"| OXIDATIVE_PHOSPHORYLATION["OXIDATIVE PHOSPHORYLATION"]
FATTY_ACID_OXIDATION -->|"implicated in"| GLYCOLYSIS["GLYCOLYSIS"]
FATTY_ACID_OXIDATION -->|"implicated in"| TCA_CYCLE["TCA CYCLE"]
FATTY_ACID_OXIDATION -->|"activates"| NEURON["NEURON"]
FATTY_ACID_OXIDATION -->|"activates"| STING["STING"]
FATTY_ACID_OXIDATION -->|"activates"| HEPATOCELLULAR_CARCINOMA["HEPATOCELLULAR CARCINOMA"]
TREM2["TREM2"] -->|"inhibits"| FATTY_ACID_OXIDATION
CPT1A["CPT1A"] -->|"regulates"| FATTY_ACID_OXIDATION
TXNIP["TXNIP"] -->|"activates"| FATTY_ACID_OXIDATION
AMPK["AMPK"] -->|"activates"| FATTY_ACID_OXIDATION
Lipid_Droplet_Mitochondria_Tet["Lipid Droplet-Mitochondria Tethering"] -->|"involved_in"| FATTY_ACID_OXIDATION
BTK["BTK"] -->|"activates"| FATTY_ACID_OXIDATION
PFKL["PFKL"] -->|"promotes"| FATTY_ACID_OXIDATION| Target | Relation | Type | Str |
|---|---|---|---|
| BDNF | produces | gene | 0.65 |
| LENVATINIB | associated_with | drug | 0.45 |
| OXIDATIVE PHOSPHORYLATION | implicated_in | process | 0.35 |
| GLYCOLYSIS | implicated_in | process | 0.35 |
| TCA CYCLE | implicated_in | process | 0.35 |
| NEURON | activates | cell_type | 0.35 |
| STING | activates | gene | 0.35 |
| HEPATOCELLULAR CARCINOMA | activates | disease | 0.35 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LENVATINIB | activates | drug | 0.65 |
| AMPK | treats | gene | 0.65 |
| HEPATOCYTES | inhibits | cell_type | 0.65 |
| AMPK | phosphorylates | gene | 0.60 |
| AMPK | inhibits | gene | 0.60 |
| AMPK | targets | gene | 0.60 |
| SIRT1 | phosphorylates | gene | 0.60 |
| SIRT1 | activates | gene | 0.60 |
| AMPK | implicated_in | gene | 0.55 |
| CANCER | implicated_in | disease | 0.35 |
| APOPTOSIS | activates | process | 0.35 |
| CANCER | activates | disease | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||