Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SMC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| AAD | associated_with | disease | 0.72 |
| FIBROBLASTS | activates | cell_type | 0.64 |
| MACROPHAGES | activates | cell_type | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| IRF3 | regulates | gene | 0.72 |
| CHROMATIN_REMODELING | regulates | phenotype | 0.64 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| C9orf72-SMCR8-WDR41 Complex Dysfunction in C9-ALS Rescued by | 0.537 | neurodegeneration | How does PIKFYVE inhibition activate unc |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-07 | 0 hypotheses
neurodegeneration | 2026-04-07 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||