gene

SRSF5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SRSF5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

6Outgoing

2Incoming

0Experiments

0Debates

Summary

SRSF5 — Serine/Arginine Rich Splicing Factor 5

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SRSF5
Full Name	Serine/Arginine Rich Splicing Factor 5
Chromosome	19q13.2
Function	The SRSF5 gene encodes a protein involved in RNA processing and splicing mechanisms critical for neuronal function and survival.
Primary Expression	various brain regions, including the cortex, hippocampus, and spinal cord, where it supports pr
Subcellular Localization	and loss of normal splicing function. Accumulation of misfolded proteins common in neurodegenerative diseases can seques
UniProt ID	Q13156
Ensembl ID	ENSG00000100650
GeneCards	SRSF5
Human Protein Atlas	SRSF5
Associated Diseases	neurodegeneration
Interactions	SOX9
KG Connections	8 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SRSF5 — AlphaFold Q13156 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SRSF5 — Serine/Arginine Rich Splicing Factor 5

gene · 626 words

→

Pathway Diagram

flowchart TD
    SRSF5(["SRSF5"])
    Aging["Aging"]
    Diabetes["Diabetes"]
    Als["Als"]
    Stem_Cell["Stem Cell"]
    T_Cell["T Cell"]
    Insulin(["Insulin"])
    AGING(["AGING"])
    SOX9(["SOX9"])
    neurodegeneration["neurodegeneration"]

    SRSF5 -->|"regulates"| Aging
    SRSF5 -->|"regulates"| Diabetes
    SRSF5 -->|"regulates"| Als
    SRSF5 -->|"regulates"| Stem_Cell
    SRSF5 -->|"regulates"| T_Cell
    SRSF5 -->|"regulates"| Insulin
    AGING -->|"regulates"| SRSF5
    SOX9 -.->|"inhibits"| SRSF5
    SRSF5 -->|"implicated in"| neurodegeneration

    style SRSF5 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (6)

Target	Relation	Type	Str
Aging	regulates	disease	0.65
Diabetes	regulates	disease	0.65
Als	regulates	disease	0.65
Stem Cell	regulates	cell_type	0.60
T Cell	regulates	cell_type	0.60
Insulin	regulates	protein	0.60

Incoming (2)

Source	Relation	Type	Str
SOX9	inhibits	gene	0.60
AGING	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SRSF5 in their description or question text

No additional research found