Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SYT11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SYT11 |
| Full Name | Synaptotagmin 11 |
| Chromosome | 1q41 |
| Protein Family | Synaptotagmin family |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Synaptic vesicles, Cytoplasm |
| Molecular Weight | 47 kDa |
| Amino Acids | 421 aa |
| Pathways | PI3K |
| UniProt ID | Q9BT88 |
| GeneCards | SYT11 |
| Human Protein Atlas | SYT11 |
| Associated Diseases | neurodegeneration |
| Interactions | PARKIN |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SYT11["SYT11"]
Als{"Als"}
SYT11 -->|"contributes_to"| Als
Parkinson{"Parkinson"}
SYT11 -->|"contributes_to"| Parkinson
ALS{"ALS"}
SYT11 -->|"contributes_to"| ALS
PARKIN["PARKIN"]
SYT11 -->|"activates"| PARKIN
PARKINSON["PARKINSON"]
SYT11 -->|"contributes_to"| PARKINSON
AND["AND"]
SYT11 -->|"activates"| AND
PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
SYT11 -->|"contributes_to"| PARKINSON_S_DISEASE
PARKINSON -->|"contributes_to"| SYT11
Substantia_Nigra["Substantia Nigra"]
SYT11 -->|"expressed_in"| Substantia_Nigra
SYT11 -->|"interacts_with"| PARKIN
neurodegeneration["neurodegeneration"]
SYT11 -->|"implicated_in"| neurodegeneration| Target | Relation | Type | Str |
|---|---|---|---|
| Als | contributes_to | disease | 0.65 |
| Parkinson | contributes_to | disease | 0.65 |
| ALS | contributes_to | disease | 0.65 |
| PARKINSON | contributes_to | gene | 0.60 |
| PARKINSON'S DISEASE | contributes_to | gene | 0.60 |
| PARKIN | activates | gene | 0.60 |
| Substantia Nigra | expressed_in | brain_region | 0.55 |
| PARKIN | interacts_with | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SYT11 in their description or question text
No additional research found