Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Sepsis-Associated Acute Kidney Injury: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | Sepsis-Associated Acute Kidney Injury |
| Key Genes/Proteins | NGAL |
Knowledge base pages for this entity
graph TD
Inflammation["Inflammation"] -->|"contributes to"| Sepsis_Associated_Acute_Kidney["Sepsis-Associated Acute Kidney Injury"]
style Inflammation fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
NGAL["NGAL"] -->|"biomarker for"| Sepsis_Associated_Acute_Kidney["Sepsis-Associated Acute Kidney Injury"]
style NGAL fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
Apoptosis["Apoptosis"] -->|"involved in"| Sepsis_Associated_Acute_Kidney["Sepsis-Associated Acute Kidney Injury"]
style Apoptosis fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Necroptosis["Necroptosis"] -->|"involved in"| Sepsis_Associated_Acute_Kidney["Sepsis-Associated Acute Kidney Injury"]
style Necroptosis fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Pyroptosis["Pyroptosis"] -->|"involved in"| Sepsis_Associated_Acute_Kidney["Sepsis-Associated Acute Kidney Injury"]
style Pyroptosis fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
style Sepsis_Associated_Acute_Kidney fill:#5d4400,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| MITOPHAGY | suppresses | process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Inflammation | contributes_to | process | 0.90 |
| NGAL | biomarker_for | protein | 0.90 |
| Apoptosis | involved_in | process | 0.85 |
| Necroptosis | involved_in | process | 0.85 |
| Pyroptosis | involved_in | process | 0.85 |
| Ferroptosis | involved_in | process | 0.85 |
| Metabolic Reprogramming | contributes_to | process | 0.85 |
| Microvascular Dysfunction | contributes_to | process | 0.85 |
| Autophagy | involved_in | process | 0.80 |
| miR-22-3p | involved_in | biomarker | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||