protein

TDP1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TDP1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

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Summary

Tyrosyl Dna Phosphodiesterase 1 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	TDP1PROTEIN
Protein Family	TDP1 Family
Protein Type	Enzyme
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	Nucleus, Cytoplasm
Molecular Weight	68 kDa
UniProt ID	Q9NZJ8
GeneCards	TDP1PROTEIN
Human Protein Atlas	TDP1PROTEIN
Protein Name	Tyrosyl-DNA Phosphodiesterase 1
Gene	TDP1
PDB IDs	3O10, 4OWD, 4OWE
Alzheimer's Disease	TDP1 mutations/dysfunction
Parkinson's Disease	TDP1 mutations/dysfunction
Spinocerebellar Ataxia (SCAN1)	TDP1 mutations/dysfunction
Associated Diseases	neurodegeneration
Interactions	PNKP, FEN1, XPF, XRCC1, SETX, HIF1A
KG Connections	43 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Tyrosyl-DNA Phosphodiesterase 1

protein · 570 words

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Pathway Diagram

graph TD
    TDP1PROTEIN["TDP1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    TDP1PROTEIN -->|"implicated_in"| neurodegeneration
    style TDP1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found