Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TGR5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| NFE2L2 | activates | gene | 0.95 |
| Neuroprotection | mediates | process | 0.90 |
| Motor Dysfunction | regulates | phenotype | 0.90 |
| Parkinson's Disease | involved_in | disease | 0.85 |
| NRF2 | activates | protein | 0.72 |
| STAT3 | activates | protein | 0.70 |
| neuron | expressed_in | cell_type | 0.70 |
| Alzheimer's disease | associated_with | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Gentiopicroside | targets | compound | 0.95 |
| GPS | activates | drug | 0.72 |
| DCA | activates | drug | 0.70 |
| Gentiopicroside | activates | compound | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||