drug

Thiabendazole

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Thiabendazole: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

11Connections

0Hypotheses

0Analyses

11Outgoing

0Incoming

No summary available yet. View on Wiki →

💊 Drug Info

Name	Thiabendazole
Key Genes/Proteins	CDK2, EGFR, P53, CHEK1
Related Diseases	liver injury, Cancer, Liver Injury

Pathway Diagram

graph TD
    Thiabendazole["Thiabendazole"] -->|"binds"| CDK2["CDK2"]
    style CDK2 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Thiabendazole["Thiabendazole"] -->|"binds"| EGFR["EGFR"]
    style EGFR fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Thiabendazole["Thiabendazole"] -->|"modulates"| P53["P53"]
    style P53 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    Thiabendazole["Thiabendazole"] -->|"causes"| liver_injury["liver injury"]
    style liver_injury fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    Thiabendazole["Thiabendazole"] -->|"causes"| Cancer["Cancer"]
    style Cancer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Thiabendazole["Thiabendazole"] -->|"binds"| CHEK1["CHEK1"]
    style CHEK1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Thiabendazole["Thiabendazole"] -->|"binds"| CDK1["CDK1"]
    style CDK1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    style Thiabendazole fill:#1b5e20,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (11)

Target	Relation	Type	Str
CDK2	binds	protein	0.90
EGFR	binds	protein	0.90
CDK2	binds_to	gene	0.88
P53	modulates	gene	0.85
liver injury	causes	phenotype	0.85
Cancer	causes	disease	0.85
Liver Injury	causes	disease	0.85
CHEK1	binds	protein	0.85
EGFR	binds_to	gene	0.85
G2/M Transition	associated_with	process	0.80
G2/M transition	modulates	process	0.80

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found