CHEK1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHEK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CHEK1 is a protein involved in neurodegeneration research. Key relationships include: associated with, regulates, implicated in. Associated with Cancer, Ms. Connected to 25 entities in the SciDEX knowledge graph.

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graph TD
    CHEK1["<b>CHEK1</b>"]
    Cancer{"Cancer"}
    CHEK1 -->|"regulates"| Cancer
    Ms{"Ms"}
    CHEK1 -->|"regulates"| Ms
    MTOR["MTOR"]
    CHEK1 -->|"associated with"| MTOR
    PIK3CA["PIK3CA"]
    CHEK1 -->|"associated with"| PIK3CA
    GSK3B["GSK3B"]
    CHEK1 -->|"associated with"| GSK3B
    AKT["AKT"]
    CHEK1 -->|"regulates"| AKT
    PARP1["PARP1"]
    CHEK1 -->|"associated with"| PARP1
    Pi3K(["Pi3K"])
    CHEK1 -->|"regulates"| Pi3K
    Akt(["Akt"])
    CHEK1 -->|"regulates"| Akt
    Mtor(["Mtor"])
    CHEK1 -->|"associated with"| Mtor
    CANCER["CANCER"]
    CHEK1 -->|"regulates"| CANCER
    CASP3["CASP3"]
    CHEK1 -->|"associated with"| CASP3
    CDK4["CDK4"]
    CDK4 -->|"associated with"| CHEK1
    CASP3 -->|"associated with"| CHEK1
    PI3K["PI3K"]
    PI3K -->|"regulates"| CHEK1
    ABL1["ABL1"]
    ABL1 -->|"associated with"| CHEK1
    ESR1["ESR1"]
    ESR1 -->|"associated with"| CHEK1
    GENES["GENES"]
    GENES -->|"associated with"| CHEK1
    PIK3CA -->|"associated with"| CHEK1
    PARP1 -->|"associated with"| CHEK1
    MTOR -->|"associated with"| CHEK1
    style CHEK1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0