Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TRANSFERRIN RECEPTOR 1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TRANSFERRIN RECEPTOR 1 |
Knowledge base pages for this entity
graph TD
TRANSFERRIN_RECEPTOR_1["TRANSFERRIN RECEPTOR 1"]
TRANSFERRIN_RECEPTOR_1 -->|"mediates"| Blood_Brain_Barrier_Penetratio["Blood-Brain Barrier Penetration"]
TRANSFERRIN_RECEPTOR_1 -->|"involved_in"| IRON_METABOLISM["IRON METABOLISM"]
TRANSFERRIN_RECEPTOR_1 -->|"binds_to"| TRANSFERRIN["TRANSFERRIN"]
TRANSFERRIN_RECEPTOR_1 -->|"expressed in"| Blood_Brain_Barrier["Blood-Brain Barrier"]
TRANSFERRIN_RECEPTOR_1 -->|"mediates"| Iron_Uptake["Iron Uptake"]
TRANSFERRIN_RECEPTOR_1 -->|"mediates"| Blood_Brain_Barrier_Crossing["Blood-Brain Barrier Crossing"]
TRANSFERRIN_RECEPTOR_1 -->|"binds"| Transferrin["Transferrin"]
TRANSFERRIN_RECEPTOR_1 -->|"mediates"| Blood_Brain_Barrier_Transport["Blood-Brain Barrier Transport"]
Bi_Htfr1["Bi-Htfr1"] -->|"binds"| TRANSFERRIN_RECEPTOR_1
Oligonucleotide_Transport_Vehi["Oligonucleotide Transport Vehicle"] -->|"binds"| TRANSFERRIN_RECEPTOR_1
TXB2["TXB2"] -->|"binds"| TRANSFERRIN_RECEPTOR_1
Bispecific_Antibodies["Bispecific Antibodies"] -->|"targets"| TRANSFERRIN_RECEPTOR_1| Target | Relation | Type | Str |
|---|---|---|---|
| IRON METABOLISM | involved_in | entity | 0.95 |
| TRANSFERRIN | binds_to | entity | 0.95 |
| Antisense Oligonucleotides | associated_with | drug | 0.90 |
| HEPATOCYTE | expressed_in | entity | 0.85 |
| DOPAMINERGIC NEURONS | involved_in | entity | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Bi-Htfr1 | binds | drug | 0.98 |
| Oligonucleotide Transport Vehicle | binds | drug | 0.95 |
| TXB2 | binds | drug | 0.95 |
| TFRC | associated_with | gene | 0.95 |
| TFRC | encodes | gene | 0.95 |
| Bispecific Antibodies | targets | drug | 0.90 |
| Bispecific Antibodies | binds | drug | 0.90 |
| New World Arenaviruses | uses | virus | 0.80 |
| Transferrin | activates | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||