entity

autophagy receptors

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about autophagy receptors: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections
2Hypotheses
2Analyses
4Outgoing
4Incoming
0Experiments
2Debates

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Outgoing (4)

TargetRelationTypeStr
Substratestargetsprotein0.95
Phagophorestransportscell_type0.90
Protein Aggregatestargetsphenotype0.90
cargo selectivityregulatesphenotype0.70

Incoming (4)

SourceRelationTypeStr
LC3interacts_withprotein0.90
PINK1recruitsgene0.90
GABARAPcomponent_ofprotein0.80
SQSTM1regulatesprotein0.50

Targeting Hypotheses (2)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
G3BP1 NTF2L Domain-Mediated mRNP Scaffold Creates Core Exclu 0.633 neurodegeneration What determines the spatial organization
Liquid-Liquid Phase Separation (LLPS) Saturation Partitionin 0.461 neurodegeneration What determines the spatial organization

Mentioning Analyses (2)

Scientific analyses that reference this entity

How do pathological stress granules in neurodegeneration escape TRIM21/autophagy

neurodegeneration | 2026-04-06 | 7 hypotheses Top: 0.717

Autophagy-lysosome pathway convergence across neurodegenerative diseases

neurodegeneration | 2026-04-01 | 12 hypotheses Top: 0.777

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (2)

Multi-agent debates referencing this entity

The study shows TRIM21 and autophagy receptors can eliminate both physiological

closed · Rounds: 4 · Score: 0.75 · 2026-04-22

Multiple NDDs converge on autophagy-lysosome dysfunction. Are there universal th

closed · Rounds: 4 · Score: 0.90 · 2026-04-06

Related Research

Hypotheses and analyses mentioning autophagy receptors in their description or question text

No additional research found