Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CHEMOTHERAPY RESISTANCE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CHEMOTHERAPY RESISTANCE |
Knowledge base pages for this entity
graph TD
CHEMOTHERAPY_RESISTANCE["CHEMOTHERAPY RESISTANCE"]
CHEMOTHERAPY_RESISTANCE -->|"inhibits"| Chemotherapy["Chemotherapy"]
CHEMOTHERAPY_RESISTANCE -->|"risk_factor_for"| Cancer["Cancer"]
Drug_Efflux["Drug Efflux"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE
Enhanced_DNA_Damage_Repair["Enhanced DNA Damage Repair"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE
Apoptosis_Evasion["Apoptosis Evasion"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE
Epigenetic_Modifications["Epigenetic Modifications"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE
Altered_Intracellular_Drug_Met["Altered Intracellular Drug Metabolism"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE
MYC["MYC"] -->|"suppression_promotes"| CHEMOTHERAPY_RESISTANCE
Cancer_Stem_Cells["Cancer Stem Cells"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE
Enhanced_Dna_Damage_Repair["Enhanced Dna Damage Repair"] -->|"contributes to"| CHEMOTHERAPY_RESISTANCE| Target | Relation | Type | Str |
|---|---|---|---|
| Chemotherapy | inhibits | drug | 0.95 |
| Cancer | risk_factor_for | disease | 0.90 |
| High-Grade Serous Ovarian Cancer | associated_with | disease | 0.88 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PRMT1 | associated_with | entity | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||