Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ferroptosis resistance: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer | associated_with | disease | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TRIM34 | mediates | gene | 0.95 |
| PI3K-AKT-mTOR | causes | pathway | 0.95 |
| SLC13A3 | promotes | gene | 0.95 |
| SIK1 | associated_with | gene | 0.95 |
| TRIM34/UPF1/GPX4 | mediates | pathway | 0.93 |
| SLC7A11 | mediates | gene | 0.90 |
| SIK1 | promotes | gene | 0.90 |
| SCD1 | mediates | protein | 0.90 |
| SREBP1 | mediates | protein | 0.90 |
| Ferroptosis Sensitivity | associated_with | phenotype | 0.85 |
| cancer stem cells | associated_with | cell_type | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Glial-Specific Ferroptosis Resistance via GPX4 Enhancement P | 0.500 | neurodegeneration | Test |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ferroptosis resistance in their description or question text
No additional research found