SREBP1

Understanding Entity Pages

This page aggregates everything SciDEX knows about SREBP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SREBP1 is a protein involved in neurodegeneration research. Key relationships include: activates, regulates, inhibits. Associated with Als, Arrhythmia, Atherosclerosis. Connected to 124 entities in the SciDEX knowledge graph.

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graph TD
    SREBP1["<b>SREBP1</b>"]
    SCD1["SCD1"]
    SREBP1 -->|"regulates"| SCD1
    FERROPTOSIS["FERROPTOSIS"]
    SREBP1 -->|"inhibits"| FERROPTOSIS
    Cancer{"Cancer"}
    SREBP1 -->|"activates"| Cancer
    Tumor{"Tumor"}
    SREBP1 -->|"activates"| Tumor
    SREBP1 -->|"inhibits"| Tumor
    Ms{"Ms"}
    SREBP1 -->|"activates"| Ms
    Als{"Als"}
    SREBP1 -->|"regulates"| Als
    SREBP1 -->|"regulates"| Ms
    SREBP1 -->|"regulates"| Tumor
    PTEN["PTEN"]
    SREBP1 -->|"activates"| PTEN
    PI3K["PI3K"]
    SREBP1 -->|"activates"| PI3K
    SREBP1 -->|"inhibits"| SCD1
    DLAT["DLAT"]
    DLAT -->|"regulates"| SREBP1
    MTORC1["MTORC1"]
    MTORC1 -->|"activates"| SREBP1
    AKT["AKT"]
    AKT -->|"activates"| SREBP1
    MTOR["MTOR"]
    MTOR -->|"activates"| SREBP1
    PI3K -->|"activates"| SREBP1
    PTEN -->|"regulates"| SREBP1
    SCD1 -->|"inhibits"| SREBP1
    OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    OXIDATIVE_STRESS -->|"activates"| SREBP1
    AMPK["AMPK"]
    AMPK -->|"activates"| SREBP1
    style SREBP1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0