Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about genomic stability: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| TP53 | enhances | gene | 0.90 |
| NPM | regulates | protein | 0.90 |
| P53 | disrupts | gene | 0.90 |
| TP53 | regulates | gene | 0.85 |
| DRAGO | regulates | gene | 0.85 |
| P53 | regulates | gene | 0.85 |
| KIAA0247 | associated_with | gene | 0.85 |
| NPM1 | regulates | protein | 0.80 |
| KIAA0247 | involved_in | gene | 0.75 |
| SIRT1 | regulates | gene | 0.70 |
| NORAD | regulates | gene | 0.70 |
| SIRT6 | maintains | gene | 0.70 |
| SIRT6 | maintains | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Conserved 5' Terminal Stem-Loop in NORAD Enables ASO-Mediate | 0.657 | molecular-biology | What are the conserved secondary structu |
Scientific analyses that reference this entity
molecular biology | 2026-04-10 | 5 hypotheses Top: 0.657
neurodegeneration | 2026-04-01 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.69 · 2026-04-21
closed · Rounds: 4 · Score: 0.88 · 2026-04-01
Hypotheses and analyses mentioning genomic stability in their description or question text
No additional research found