Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DRAGO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | DRAGO |
| Key Genes/Proteins | KIAA0247, TP53, P53 |
| Related Diseases | TUMOR, Cell Growth Suppression |
Knowledge base pages for this entity
graph TD
DRAGO["DRAGO"]
DRAGO -->|"interacts"| TP53["TP53"]
DRAGO -->|"involved_in"| DNA_Damage_Response["DNA Damage Response"]
DRAGO -->|"involved_in"| Tumor_Suppression["Tumor Suppression"]
DRAGO -->|"involved_in"| Oncosuppression["Oncosuppression"]
DRAGO -->|"causes"| Cell_Growth_Suppression["Cell Growth Suppression"]
DRAGO -->|"causes"| Cell_Death["Cell Death"]
DRAGO -->|"regulates"| Genomic_Stability["Genomic Stability"]
DRAGO -->|"involved_in"| Apoptosis["Apoptosis"]
TP53 -->|"upregulates"| DRAGO
DNA_Damaging_Agents["DNA Damaging Agents"] -->|"upregulates"| DRAGO
GENES["GENES"] -->|"activates"| DRAGO
DNA["DNA"] -->|"activates"| DRAGO
P53["P53"] -->|"activates"| DRAGO
KIAA0247["KIAA0247"] -->|"activates"| DRAGO
AUTOPHAGY["AUTOPHAGY"] -->|"activates"| DRAGO| Target | Relation | Type | Str |
|---|---|---|---|
| KIAA0247 | associated_with | gene | 1.00 |
| TP53 | interacts_with | gene | 0.95 |
| DNA Damage Response | involved_in | process | 0.95 |
| Tumor Suppression | involved_in | process | 0.90 |
| Oncosuppression | involved_in | process | 0.90 |
| TUMOR | suppresses | disease | 0.90 |
| Cell Growth Suppression | causes | phenotype | 0.85 |
| Cell Death | causes | process | 0.85 |
| Genomic Stability | regulates | process | 0.85 |
| Apoptosis | involved_in | process | 0.80 |
| Tumor Suppression | mediates | process | 0.80 |
| P53 | cooperates_with | protein | 0.80 |
| Cell Integrity | involved_in | process | 0.75 |
| Tumor | inhibits | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| Aging | activates | disease | 0.65 |
| Autophagy | activates | pathway | 0.60 |
| Apoptosis | activates | pathway | 0.60 |
| MIRNAS | regulates | gene | 0.60 |
| P53 | activates | gene | 0.60 |
| KIAA0247 | activates | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| Ras | activates | protein | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TP53 | upregulates | gene | 0.95 |
| DNA Damaging Agents | upregulates | compound | 0.90 |
| DNA-Damaging Agents | upregulates | compound | 0.85 |
| GENES | activates | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| P53 | activates | gene | 0.60 |
| KIAA0247 | activates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| MIRNAS | regulates | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||