Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about oxidative_stress_response: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| apoptosis | activates | phenotype | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NRF2 | regulates | gene | 0.87 |
| thiol_redox_switches | regulates | pathway | 0.72 |
| ROS | activates | phenotype | 0.72 |
| ROS | participates_in | phenotype | 0.72 |
| NRF2 | regulates | protein | 0.72 |
| NRF2_pathway | mediates | pathway | 0.70 |
| NFKB | regulates | gene | 0.64 |
| FOXO3 | regulates | gene | 0.64 |
| DUBS | participates_in | protein | 0.64 |
| transcriptional_regulators | regulates | protein | 0.64 |
| chaperones | participates_in | protein | 0.56 |
| SLC7A11 | participates_in | gene | 0.56 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| NRF2-Mediated Proteostatic Convergence: Shared Oxidative Str | 0.700 | neurodegeneration | - |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 14 hypotheses Top: 0.732
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.69 · 2026-04-12
closed · Rounds: 7 · Score: 0.91 · 2026-04-10
Hypotheses and analyses mentioning oxidative_stress_response in their description or question text
No additional research found