🧫

Resveratrol protection against renal I/R injury in diabetic rats

active
experiment Created: 2026-04-11T00:45:03 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-8b61762b-2663-4111-9e71-d
🧫 Experiment Protocol Animal Modelproposed
Related Entities
NFE2L2, HMOX1, TLR4, NFKB1
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:45:03.104229'}
p_valueNone
protocolStreptozotocin induction of diabetes in rats, resveratrol pretreatment, renal ischemia/reperfusion induction, assessment of renal function, oxidative stress markers, inflammatory responses, apoptosis,
effect_sizeNone
sample_sizeNone
source_pmid41958068
extracted_at2026-04-10T17:45:03.101026
_schema_version1
experiment_typeanimal_model
success_criteriaSignificant improvement in renal function parameters, reduced oxidative stress markers, decreased inflammatory responses and apoptosis, increased Nrf2/HO-1 expression, decreased TLR4/NF-κB expression,
expected_outcomesRSV treatment expected to improve renal function, reduce oxidative stress and inflammation, decrease apoptosis, increase Nrf2/HO-1 expression, and decrease TLR4/NF-κB expression. ML385 treatment expec
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
25
Outgoing
12
0 supporting 0 contradicting 0 neutral
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