C4B

C4B Protein

Score: 0.548 Price: $0.49 Medium Druggability Status: active

HYPOTHESES

PAPERS

KG EDGES

DEBATES

3D Protein Structure

🧬 C4B — PDB 4FXK Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Druggability & Clinical Context

Druggability

Medium

Score: 0.50

Clinical Stage

Phase I

Target Class

Protein

Safety

0.50

Druggability Analysis

Drug Development0.00

Structural Tractability0.30

Target Class0.50

Safety Profile0.50

Key Metrics

PDB Structures:

Known Drugs:

Approved:

In Clinical Trials:

Therapeutic Areas:

neurodegeneration

Mechanism: Prioritized from 1 SciDEX hypotheses, including: Age-Dependent Complement C4b Upregulation Drives Synaptic Vulnerability in Hippocampal CA1 Neurons

Known Drugs:

No known drugs targeting this protein

Structural Data:

🧬 3D Protein Structure

🧬 C4B — PDB 4FXK Click to expand interactive 3D viewer

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (1)

Age-Dependent Complement C4b Upregulation Drives Synaptic Vulnerability in Hippocampal CA1 Neurons0.470

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Knowledge Graph (20)

Debate History (0)

No debates yet

C4B

3D Protein Structure

Druggability & Clinical Context

🧬 3D Protein Structure

Linked Hypotheses (1)

Linked Experiments (0)

Scoring Dimensions

Knowledge Graph (20)

activates (1)

associated with (3)

biomarker for (2)

component of (1)

expressed in (2)

induced by (1)

interacts with (1)

mediates (1)

participates in (1)

pathology linked to (1)

pathway partner (1)

regulated by (2)

regulates (1)

repressed by (1)

therapeutic target of (1)

Debate History (0)