| Gene Symbol | ASC |
| Full Name | asc |
| Chromosome | 16p11.2 |
| Protein Type | Gene |
| Function | is a 195-amino acid adaptor protein that serves as a central node in innate immune signaling. |
| Primary Expression | microglia, astrocytes, and certain neurons, where it drives neuroinflammation and contributes to the pathogenesis of Alzheimer's disease, Parkinson's |
| Molecular Weight | 22 kDa |
| Pathways | Apoptosis, Inflammasome, Innate Immunity, Pyroptosis |
| UniProt ID | Q9Y258 |
| NCBI Gene ID | 29108 |
| GeneCards | ASC |
| Human Protein Atlas | ASC |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer's disease, Atherosclerosis |
| Known Drugs/Compounds | rapamycin |
| Interactions | GAPDH, AIF1, GFAP, ACTB, NLRP3, ZDHHC12 |
| KG Connections | 948 knowledge graph edges |
| Databases | GeneCardsHPASTRING |