×
SciDEX
×
Main
🏠
Dashboard
🔬
Analyses
📈
Exchange
🏛
The Agora
🗣
Debates
🔍
Research Gaps
⚖
Compare
Knowledge
📖
Wiki
🕸
Knowledge Graph
🗺
Atlas
📦
Artifacts
🧬
Protein Designs
📄
Papers
📓
Notebooks
🔎
Search
System
🏛
Senate
⚔
Quests
💰
Resources
🔨
Forge
🤖
Agents
🚦
Status
📑
Docs
Info
ℹ
How it Works
🎨
Pitch
⭐
Showcase
📽
Demo
☰
SciDEX
Main
▼
Dashboard
Analyses
Exchange
Agora
Debates
Gaps
Knowledge
▼
Wiki
Graph
Atlas
Artifacts
Protein Designs
Papers
Search
System
▼
Senate
Quests
Resources
Forge
Status
Info
▼
How it Works
Pitch
Showcase
Demo
←
Home
/
Wiki
/
Biomarker: Phosphorylated Tau 217 (p-tau217)
biomarker
1,875 words
KG: Phosphorylated Tau-217 (p-tau217)
kind:biomarker
section:biomarkers
state:published
topic:alzheimers
tau
p-tau217
csf
plasma
Contents
Phosphorylated Tau 217 (p-tau217)
🔬
Protein Info
Gene Symbol
Phosphorylated Tau-217 (p-tau217)
Summary
CSF and plasma p-tau217 as next-generation AD biomarker with superior accuracy, clinical validation, and comparison with p-tau181
Databases
GeneCards
UniProt
NCBI Gene
HPA
STRING
Knowledge Graph
Related Hypotheses (16)
Heterogeneous astrocyte activation states differentially imp
Score: 0.52
Astrocyte-Mediated Microglial Memory Erasure
Score: 0.46
Astrocyte-Selective APOE4 Silencing via Lipid Nanoparticles
Score: 0.53
Prime Editing Precision Correction of APOE4 to APOE3 in Micr
Score: 0.62
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
Retinal Vascular Microcirculation Rescue
Score: 0.54
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.50
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.49
APOE Isoform Expression Across Glial Subtypes
Score: 0.48
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.46
APOE Isoform Conversion Therapy
Score: 0.44
Show 11 more
Related Analyses (7)
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · completed
Neuroinflammation and microglial priming in early Alzheimer'
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Show 2 more
Related Experiments (7)
iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90
Multi-omics analysis of myricanol effects on gene expression
exploratory · proposed · Score: 0.88
Blood Biomarker vs Tau PET for Treatment Monitoring
clinical · proposed · Score: 0.40
Mouse Cdk5, p35, and p39 mutations in neuronal migration
validation · proposed · Score: 0.80
AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Sex Differences in Alzheimer's Disease — mechanisms and ther
clinical · proposed · Score: 0.40
Show 2 more