| Gene Symbol | EXOSOMALMIR155 |
| Function | ### Pro-inflammatory Activation |
| Neuroinflammation | miR-155 promotes pro-inflammatory cytokine production in microglia |
| Amyloid processing | Alters amyloid precursor protein (APP) metabolism |
| Tau pathology | Modulates tau phosphorylation pathways |
| Synaptic dysfunction | Impairs synaptic plasticity and memory formation |
| Dopaminergic neurons | Affected neurons show miR-155 upregulation |
| Microglia | Promotes neuroinflammation via NF-κB pathway |
| Peripheral blood | Exosomal miR-155 distinguishes PD from healthy controls |
| Autoimmune demyelination | miR-155 regulates T-cell differentiation |
| Blood-brain barrier disruption | Increases endothelial permeability |
| Microglial activation | Perpetuates inflammatory lesions |
| Non-invasive testing | Easy sample collection |
| High sensitivity | Detects early-stage disease |
| Disease specificity | Distinguishes AD from PD and other dementias |
| Prognostic value | Correlates with disease severity |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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