| Gene Symbol | GLUTAMATE |
| Complementary to protein biomarkers | Glutamate provides orthogonal information to Aβ (A) and tau (T) markers |
| Network dysfunction assessment | Captures hyperexcitability not reflected in structural biomarkers |
| Therapeutic monitoring | Anti-excitotoxic treatments should show glutamate normalization |
| Prognostic value | Elevated glutamate predicts progression in AD, PD, and ALS |
| Associated Diseases | COGNITIVE DECLINE, EPILEPSY, EXCITOTOXICITY, FERROPTOSIS, GLUTAMATE EXCITOTOXICITY, GLYCOLYSIS |
| Known Drugs/Compounds | KETAMINE |
| Interactions | PARKIN, PINK1, PTEN, UBIQUITIN, AMPK, TAU |
| KG Connections | 505 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |