biomarker 1,195 words KG: ALZHEIMERS 2026-03-24
kind:biomarkersection:biomarkersstate:publishedevidence:strong
Contents

Olfactory Biomarkers for Alzheimer's Disease

🔬 Protein Info
Gene Symbolalzheimers
Aliasesalzheimers
PreclinicalSubtle odor identification deficits, normal threshold
MCIImpaired odor identification and discrimination
Mild ADReduced odor memory, olfactory threshold changes
Moderate-SevereAnosmia or severe hyposmia
Associated DiseasesALZHEIMER
KG Connections7 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (18)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.66
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52

Related Analyses (20)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
TREM2 agonism vs antagonism in DAM microglia
neurodegeneration · failed

Related Experiments (30)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Brain Connectivity-Targeted tACS Trial in Early AD
clinical · proposed · Score: 0.95
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.90

See Also (15)

TREM2 Agonist Therapies for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Tau Immunotherapy for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Sodium Oligomannate (GV-971) for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Siponimod for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Nanomedicine Approaches to Alzheimer's Disease
therapeutic · Pages share 18 hypotheses

Knowledge Graph (6 edges)

ALZHEIMERS activates WAM
TREM2 associated_with ALZHEIMERS
SERPINA3N associated_with ALZHEIMERS
R47H_TREM2 contributes_to ALZHEIMERS
DAM associated_with ALZHEIMERS
MICROGLIA participates_in ALZHEIMERS