biomarker 1,884 words KG: Eeg 2026-03-24
kind:biomarkersection:biomarkersstate:published
Contents

EEG Biomarkers for Alzheimer's Disease

🔬 Protein Info
Gene SymbolEeg
Neuronal lossreduced cortical activity
Synaptic dysfunctionaltered connectivity
Network disruptionchanged synchronization patterns
Slowing of background activityincreased delta/theta, decreased alpha/beta
Reduced coherencedisrupted cortical connectivity
Clinical significanceCorrelates with disease severity
Diagnostic valueStrongest discriminator between AD and controls
Sensitivity70-85%, **Specificity**: 75-90%
Key markerPosterior alpha slowing
Clinical relevanceAssociated with cognitive performance
KG Connections1 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (27)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.66
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52

Related Analyses (20)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
TREM2 agonism vs antagonism in DAM microglia
neurodegeneration · failed

Related Experiments (30)

tACS Connectivity Trial in Early Alzheimer's
clinical · proposed · Score: 0.40
Cholinergic System Dysfunction in DLB — Mechanisms and Thera
clinical · proposed · Score: 0.40
DLB Cognitive Fluctuation Mechanism Experiment
clinical · proposed · Score: 0.40
DLB Treatment Response Biomarkers — Predicting Cholinesteras
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

TREM2 Agonist Therapies for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Tau Immunotherapy for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Sodium Oligomannate (GV-971) for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Siponimod for Alzheimer's Disease
therapeutic · Pages share 18 hypotheses
Nanomedicine Approaches to Alzheimer's Disease
therapeutic · Pages share 18 hypotheses

Knowledge Graph (1 edges)

Eeg biomarker_for Drug-Resistant Epilepsy