mechanism 2,517 words KG: cellular_senescence 2026-03-31
evidence:strongmechanismmechanismspublishedsenescencesaspbrain-agingsenolyticneuroinflammationalzheimerparkinson
Contents

Cellular Senescence in Brain Aging and Neurodegeneration

Mechanism Info
NameCellular Senescence in Brain Aging and Neurodegeneration
Categoryevidence:strong
SummaryComprehensive mechanism page covering cellular senescence pathways in brain aging, including SASP, senolytics, and therapeutic targeting in AD, PD, and other neurodegenerative disorders
Key Genes/ProteinsPGAM5, mTOR, IRF, CDKN2A
Related Diseasescardiac_aging, myocardial_ischemia
Linked Hypotheses3 hypotheses

Knowledge Graph