PGAM5

Understanding Entity Pages

This page aggregates everything SciDEX knows about PGAM5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PGAM5 is a concept in neurodegeneration research. Key relationships include: interacts with, regulates, implicated in. Associated with AD, ALI, ALS. Connected to 187 entities in the SciDEX knowledge graph.

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graph TD
    PGAM5["PGAM5"]
    PGAM5 -->|"regulates"| DRP1["DRP1"]
    PGAM5 -->|"interacts"| Alzheimer["Alzheimer"]
    PGAM5 -->|"interacts"| ALS["ALS"]
    PGAM5 -->|"interacts"| Frontotemporal_Dementia["Frontotemporal Dementia"]
    PGAM5 -->|"interacts"| Dementia["Dementia"]
    PGAM5 -->|"interacts"| Cardiovascular["Cardiovascular"]
    PGAM5 -->|"interacts"| Parkinson["Parkinson"]
    PGAM5 -->|"regulates"| Senescence["Senescence"]
    PGAM5 -->|"activates"| mitochondrial_fission["mitochondrial_fission"]
    PGAM5 -->|"inhibits"| cellular_senescence["cellular_senescence"]
    BCL2L11["BCL2L11"] -->|"interacts"| PGAM5
    DNA["DNA"] -->|"interacts"| PGAM5
    NIX["NIX"] -->|"interacts"| PGAM5
    HIF1["HIF1"] -->|"interacts"| PGAM5
    RB1["RB1"] -->|"interacts"| PGAM5
    NLRP3["NLRP3"] -->|"interacts"| PGAM5
    PARKINSON["PARKINSON"] -->|"interacts"| PGAM5
    FMR1["FMR1"] -->|"interacts"| PGAM5
    RB1CC1["RB1CC1"] -->|"interacts"| PGAM5
    PARL["PARL"] -->|"interacts"| PGAM5