Contents

DNAJC10 Gene

🧬 Gene Info

Gene Symbol	DNAJC10
Full Name	DnaJ Heat Shock Protein Family (Hsp40) Member C10
Aliases	ERdj5
Protein Type	Chaperone
Function	DNAJC10/ERdj5 possesses multiple domains and functions
Primary Expression	cortex, hippocampus, and various brain regions - Cellular Localization: ER lumen, with some
Subcellular Localization	the endoplasmic reticulum (ER) where it plays critical roles in protein folding, quality control, and ER-associated degr
Molecular Weight	90.6 kDa
Amino Acids	70 aa
GeneCards	DNAJC10
Human Protein Atlas	DNAJC10
J Domain	Binds to Hsp70 family proteins and stimulates their ATPase activity
Client Binding Domain	Recognizes and binds to misfolded proteins
Thioredoxin Domains	Contains two thioredoxin-like domains with redox activity
ER Localization	Contains an ER retention signal (KDEL or RDEL)
Associated Diseases	neurodegeneration
KG Connections	40 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Knowledge Graph