| Gene Symbol | ADARB1 |
| Aliases | ADAR2 |
| Chromosome | 21q22.3 [@mannion2019] |
| Function | The ADARB1 gene encodes adenosine deaminase acting on RNA 2 (ADAR2), an enzyme that catalyzes the deamination of adenosine to inosine (A-to-I editing) in double-stranded RNA. |
| Primary Expression | neurons but not in glial cells |
| Molecular Weight | 70 kDa |
| Amino Acids | 739 aa |
| UniProt ID | P78563 |
| NCBI Gene ID | 104 |
| Ensembl ID | ENSG00000101850 |
| GeneCards | ADARB1 |
| Human Protein Atlas | ADARB1 |
| Disease | Variant/Region |
| Amyotrophic Lateral Sclerosis | Reduced ADAR2 activity |
| Aicardi-Goutières Syndrome | Biallelic mutations |
| Associated Diseases | Amyotrophic Lateral Sclerosis, Aicardi-Goutières Syndrome, Huntington's Disease, Bipolar Disorder, Schizophrenia |
| Databases | GeneCardsHPASTRING |