| Gene Symbol | DRPLA |
| Full Name | Dentatorubral-Pallidoluysian Atrophy |
| Chromosome | 12p13.31 |
| Function | Atrophin-1 functions as a transcriptional co-repressor: - Interacts with histone deacetylases (HDACs) - Represses transcription through histone hypoacetylation - Modulates nuclear receptor signaling - |
| Primary Expression | Ubiquitous, highest in brain (cerebellum, basal ganglia) |
| Amino Acids | 190 aa |
| Exons | 10 |
| UniProt ID | P55072 |
| NCBI Gene ID | 1785 |
| GeneCards | DRPLA |
| Human Protein Atlas | DRPLA |
| Associated Diseases | Huntington, Huntington's disease |
| KG Connections | 21 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!