gene 990 words KG: FASLG 2026-03-24
kind:genesection:genesstate:published
Contents

FASLG - Fas Ligand

🧬 Gene Info
Gene SymbolFASLG
Full NameFASLG - Fas Ligand
Chromosome1q24.3
Protein TypeGene
Functionis a gene encoding the Fas ligand (FasL/CD95L), a Type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily.
Primary Expressionvarious tissues with notable patterns relevant to neurodegeneration: [@yang2006]
Molecular Weight26 kDa
PathwaysNF-κB
UniProt IDP48023
NCBI Gene ID3564
GeneCardsFASLG
Human Protein AtlasFASLG
Associated Diseasesneurodegeneration
KG Connections1 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (12)

Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: mediates
Neurodegeneration
disease · KG edge: implicated_in
ALS Therapeutic Landscape — Programs by Phase and Modal
disease · Pages share 3 hypotheses
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses

Knowledge Graph (1 edges)

FASLG mediates Apoptosis