gene 990 words KG: FASLG
Contents

FASLG - Fas Ligand

🧬 Gene Info
Gene SymbolFASLG
Full NameFas Ligand
Chromosome1q24.3
Protein TypeGene
Functionis a gene encoding the Fas ligand (FasL/CD95L), a Type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily.
Primary Expressionvarious tissues with notable patterns relevant to neurodegeneration: [@yang2006]
Molecular Weight26 kDa
PathwaysNF-κB
UniProt IDP48023
NCBI Gene ID3564
GeneCardsFASLG
Human Protein AtlasFASLG
Associated Diseasesneurodegeneration
KG Connections1 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (12)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
APOE Isoform Conversion Therapy
Score: 0.72
Membrane Cholesterol Gradient Modulators
Score: 0.71

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: mediates
Alpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypotheses
Cell-Free DNA Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

Knowledge Graph (1 edges)

FASLG mediates Apoptosis

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