| Gene Symbol | NADK |
| Protein Type | Kinase |
| Function | NADK encodes NAD kinase, the enzyme that catalyzes NADP+ biosynthesis from NAD+. |
| Pathways | Mapk, Immune Response |
| Ensembl ID | ENSG00000008130 |
| GeneCards | NADK |
| Human Protein Atlas | NADK |
| Antioxidant defense | NADPH provides reducing equivalents for glutathione reductase and NADPH oxidase |
| Biosynthetic reactions | Fatty acid synthesis, cholesterol synthesis, and nucleotide synthesis require NADPH |
| DNA repair | PARP activity consumes NAD+, and NADPH supports repair processes |
| Immune response | NADPH oxidase in phagocytic cells generates reactive oxygen species for microbial killing |
| Associated Diseases | neurodegeneration |
| Interactions | CYTOKINES, INPP5D, PROINFLAMMATORY CYTOKINES, RIPK1 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!