| Gene Symbol | RARB |
| Aliases | Retinoic Acid Receptor Beta |
| Chromosome | 3p24.2 |
| Protein Type | Receptor |
| Function | encodes a nuclear receptor that functions as a ligand-activated transcription factor for retinoic acid (RA), the active metabolite of vitamin A. |
| Primary Expression | numerous tissues including brain, lung, skin, and developing embryonic tissues |
| Amino Acids | 465 aa |
| Exons | 10 |
| Pathways | Notch, Wnt |
| Ensembl ID | ENSG00000177030 |
| GeneCards | RARB |
| Human Protein Atlas | RARB |
| N-terminal activation domain (AF-1) | Contains ligand-independent transcriptional activation function |
| DNA-binding domain (DBD) | Two zinc finger motifs that recognize RAREs in target gene promoters |
| Hinge region | Flexible domain connecting DBD to LBD, contains nuclear localization signals |
| Associated Diseases | neurodegeneration |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |