gene 1,656 words KG: SNCG 2026-03-27
kind:genesection:genestopic:parkinsonstopic:alzheimersstate:published
Contents

SNCG Gene — Gamma-Synuclein

🧬 Gene Info
Gene SymbolSNCG
Full NameGamma-Synuclein
Chromosome10q23.2-q23.3
Protein FamilySynuclein (alpha, beta, gamma)
Functionencodes gamma-synuclein (also known as synoretin or BCSG1), the third member of the synuclein family of proteins
Primary Expressionthe nervous system and has been implicated in various neurodegenerative processes
Molecular Weight13.0 kDa
Amino Acids127 aa
UniProt IDP37841
NCBI Gene ID6623
Ensembl IDENSG00000173267
OMIM162267
GeneCardsSNCG
Human Protein AtlasSNCG
Alpha-synuclein (SNCA)The most studied member, central to Parkinson's disease pathogenesis
Associated Diseasesneurodegeneration
KG Connections24 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (7)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.49
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.45

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (10)

Proteins
index · KG edge: expressed_in
STMN1 — Stathmin 1
gene · KG edge: expressed_in
SNCB Gene
gene · KG edge: expressed_in
NDUFS6 Gene
gene · KG edge: expressed_in
MAPT (Microtubule-Associated Protein Tau) Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

SNCG expressed_in STMN1
SNCG expressed_in GAP43
SNCG expressed_in HSPE1
SNCG expressed_in MAPT
SNCG expressed_in NDUFS6
SNCG expressed_in Temporal Lobe
SNCG expressed_in Frontal Lobe
SNCG expressed_in BRAIN INJURY
SNCG expressed_in AND
SNCG expressed_in LDHB