protein

IKBA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IKBA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections

0Hypotheses

0Analyses

5Outgoing

4Incoming

0Experiments

No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	IKBA
GeneCards	IKBA
Human Protein Atlas	IKBA
Interactions	NF-κB, RELA, NFKB, ABLIM1
KG Connections	9 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (5)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    IKBA["IKBA"] -.->|"inhibits"| NF__B["NF-kappaB"]
    style NF__B fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    IKBA["IKBA"] -->|"interacts"| NFKB["NFKB"]
    style NFKB fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    IKBA["IKBA"] -.->|"suppresses"| NFKB1["NFKB1"]
    style NFKB1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    IKBA["IKBA"] -.->|"inhibits"| RELA["RELA"]
    style RELA fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TGM2["TGM2"] -->|"substrate of"| IKBA["IKBA"]
    style TGM2 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    ABLIM1["ABLIM1"] -->|"binds"| IKBA["IKBA"]
    style ABLIM1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    UBIQUITIN["UBIQUITIN"] -->|"modulates"| IKBA["IKBA"]
    style UBIQUITIN fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Rhein["Rhein"] -->|"regulates"| IKBA["IKBA"]
    style Rhein fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    style IKBA fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (5)

Target	Relation	Type	Str
NF-κB	inhibits	protein	0.90
NFKB	interacts_with	protein	0.90
NFKB	inhibits	protein	0.90
NFKB1	suppresses	protein	0.90
RELA	inhibits	protein	0.85

Incoming (4)

Source	Relation	Type	Str
ABLIM1	binds_to	protein	0.95
UBIQUITIN	modulates	protein	0.93
ABLIM1	phosphorylates	protein	0.90
Rhein	downregulates	compound	0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

IKBA

Understanding Entity Pages

Wiki Pages (5)

NF-kB Pathway Inhibition Therapy for Neurodegeneration

NF-κB p105 Protein

NF-κB p105/p50 Protein

RELA (NF-κB p65)