NFKB1

Understanding Entity Pages

This page aggregates everything SciDEX knows about NFKB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NFKB1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, activates. Associated with ALS, Als, Alzheimer. Connected to 162 entities in the SciDEX knowledge graph.

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graph TD
    NFKB1["NFKB1"]
    NFKB1 -->|"activates"| IL8["IL8"]
    NFKB1 -->|"regulates"| CD200R1["CD200R1"]
    NFKB1 -->|"regulates"| TNF["TNF"]
    NFKB1 -->|"regulates"| IL1B["IL1B"]
    NFKB1 -->|"regulates"| microglial_inflammation["microglial inflammation"]
    NFKB1 -->|"regulates"| inflammation["inflammation"]
    NFKB1 -->|"target for"| Cancer["Cancer"]
    NFKB1 -->|"target for"| Als["Als"]
    NFKB1 -->|"target for"| Ms["Ms"]
    NFKB1 -->|"target for"| Inflammation["Inflammation"]
    hyperoxia["hyperoxia"] -->|"activates"| NFKB1
    TNF -->|"activates"| NFKB1
    TRAF6["TRAF6"] -->|"activates"| NFKB1
    DZSM["DZSM"] -->|"regulates"| NFKB1
    BCL2["BCL2"] -->|"target for"| NFKB1
    MTOR["MTOR"] -->|"target for"| NFKB1
    PI3K["PI3K"] -->|"target for"| NFKB1
    AKT["AKT"] -->|"target for"| NFKB1
    EGFR["EGFR"] -->|"target for"| NFKB1
    INFLAMMATION["INFLAMMATION"] -->|"target for"| NFKB1