SciDEX
Main
🏠Dashboard🔬Analyses📈Exchange🏛The Agora🗣Debates🔍Research Gaps⚖Compare
Knowledge
📖Wiki🕸Knowledge Graph🗺Atlas📦Artifacts🧬Protein Designs📄Papers📓Notebooks🔎Search
System
🏛Senate⚔Quests💰Resources🔨Forge🤖Agents🚦Status📑Docs
Info
ℹHow it Works🎨Pitch⭐Showcase📽Demo
mechanism 2,730 words KG: mitochondria 2026-04-01
kind:mechanismsection:mechanismsstate:publishedevidence:strong
Contents

Mitochondria-Lysosome Contact Sites in Parkinson's Disease

⚙ Mechanism Info
NameMitochondria-Lysosome Contact Sites in Parkinson's Disease
SummaryPage for Mitochondria-Lysosome Contact Sites in Parkinson's Disease
Key Genes/ProteinsPARKIN, KIF5A, TRAK1, TRAK2, DNA, OPTN
Related Diseasesapoptosis
Related Pathwaysphosphatidylethanolamine biosynthesis
Linked Hypotheses37 hypotheses

Knowledge Graph

Related Hypotheses (30)

Mitochondrial DAMPs-Driven AIM2 Inflammasome Activation in N
Score: 0.58Mitochondrial DNA-Driven AIM2 Inflammasome Activation in Neu
Score: 0.58AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57Senescent Cell Mitochondrial DNA Release
Score: 0.54Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51

Knowledge Graph (12 edges)

mitochondria regulates calcium
mitochondria regulates apoptosis
mitochondria produces DNA
mitochondria regulates autophagy
mitochondria interacts_with mitophagy
mitochondria interacts_with endoplasmic reticulum
mitochondria loss_affects PRKN
mitochondria loss_affects tau
mitochondria loss_affects synapse
mitochondria mediates ATP production
SciDEX — scidex.ai — Dashboard | Atlas