protein 1,967 words KG: AXIN2PROTEIN 2026-03-27
kind:proteinsection:proteinsstate:published
Contents

AXIN2 Protein

🔬 Protein Info
Gene SymbolAXIN2
AliasesAXIN2PROTEIN
Chromosome17q24.1
Protein TypeGene
Functionis a critical negative regulator of the Wnt/beta-catenin signaling pathway.
Primary Expressionneural stem cells (NSCs) in the adult subventricular zone (SVZ) and dentate gyrus subgranular zone (SGZ):
Subcellular LocalizationCytoplasm, nucleus
Molecular Weight88 kDa
Amino Acids778 aa
PathwaysWnt, Wnt signaling, Wnt pathway
UniProt IDQ9Y2T1
NCBI Gene ID8313
Ensembl IDENSG00000168646
GeneCardsAXIN2
Human Protein AtlasAXIN2
Associated DiseasesCancer, Carcinoma
Known Drugs/Compoundsrapamycin
InteractionsP62, MYC, MKI67, WIF1, AND, CCND1
KG Connections256 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph