| Gene Symbol | CYP7B1 |
| Full Name | Cytochrome P450 7B1 (Oxysterol 7-alpha-hydroxylase) |
| Aliases | Page for CYP7B1 Gene, Page for CYP7B1 Protein |
| Chromosome | 8q12.3 |
| Protein Family | Cytochrome P450 family |
| Function | Cholesterol to 7-alpha-hydroxycholesterol: Rate-limiting step in bile acid synthesis |
| Primary Expression | Liver, Brain, Kidney, Testis, Spinal cord |
| Subcellular Localization | Endoplasmic reticulum (membrane-bound) |
| Molecular Weight | ~58 kDa (513 aa) |
| Pathways | Cholesterol, Lipid Metabolism |
| UniProt ID | O76074 |
| NCBI Gene ID | 9420 |
| Ensembl ID | ENSG00000172817 |
| OMIM | 603711 |
| GeneCards | CYP7B1 |
| Human Protein Atlas | CYP7B1 |
| Associated Diseases | Alzheimer |
| Interactions | CYP46A1, TNF, ALZHEIMER, ROS, IL-6, IL-17 |
| KG Connections | 40 knowledge graph edges |
| Databases | GeneCardsHPASTRING |