| Gene Symbol | DOCK3 |
| Full Name | Dedicator of Cytokinesis 3 |
| Aliases | Page for DOCK3, Page for DOCK3 Protein |
| Chromosome | 3p21.2 |
| Function | Rac1 Activation: DOCK3 activates Rac1, a key regulator of actin cytoskeleton dynamics [2] |
| Primary Expression | Cerebral cortex, Hippocampus, Motor neurons, Spinal cord |
| Molecular Weight | ~220 kDa |
| Pathways | PI3K, PI3K signaling, Wnt Signaling |
| UniProt ID | Q9UPJ4 |
| NCBI Gene ID | 1786 |
| Ensembl ID | ENSG00000157617 |
| OMIM | 607337 |
| GeneCards | DOCK3 |
| Human Protein Atlas | DOCK3 |
| Domain Organization | Contains DOCK homology region (DHR) domains |
| Associated Diseases | Amyotrophic Lateral Sclerosis, Parkinson's Disease, Neurodegeneration |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, APP, APP/PS1, ERBB4 |
| KG Connections | 19 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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