| Gene Symbol | DYNACTIN |
| Aliases | DYNACTINPROTEIN |
| Protein Family | Dynactin family |
| Function | Dynein alone exhibits relatively short "runs" along microtubule tracks, typically moving only 0.5-1 μm before dissociating [13]. |
| Molecular Weight | 150 kDa |
| Pathways | Axonal Transport, Autophagy, Cholesterol |
| UniProt ID | Q14203 |
| GeneCards | DYNACTIN |
| Human Protein Atlas | DYNACTIN |
| Retrograde axonal transport | Movement of cargo from nerve terminal to cell body |
| Lysosomal and endosomal trafficking | Positioning and movement of degradative organelles |
| Mitochondrial distribution | Maintaining proper mitochondrial positioning in neurons |
| Protein aggregate clearance | Transporting misfolded proteins and aggregates toward the cell body for degradation |
| Synapse formation and function | Regulating presynaptic assembly and postsynaptic receptor trafficking |
| Cell division | Mitotic spindle orientation and chromosome positioning |
| Associated Diseases | neurodegeneration |
| Interactions | Actin, AUTOPHAGY, AXON, DCTN1, Dynein, DYNEIN |
| KG Connections | 38 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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