| Gene Symbol | ERCC3PROTEIN |
| Chromosome | 19q13.2 |
| Function | is a critical DNA helicase and ATP-dependent 3'-5' translocase that functions as a core component of the TFIIH (Transcription Factor II H) complex. |
| Subcellular Localization | ** | Nucleus | |
| Molecular Weight | 89 kDa |
| Amino Acids | 782 aa |
| GeneCards | ERCC3PROTEIN |
| Human Protein Atlas | ERCC3PROTEIN |
| UV-induced lesions | Cyclobutane pyrimidine dimers (CPDs), 6-4 photoproducts |
| Chemical adducts | Benzo[a]pyrene diol epoxide (BPDE) adducts |
| Oxidative damage | Certain oxidized bases |
| Crosslinks | DNA interstrand crosslinks |
| Associated Diseases | Als, Carcinoma, Cirrhosis |
| Interactions | AKT, CCL2, CEBPB, CHKA, CYP1A2, CYP3A4 |
| KG Connections | 42 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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