CCL2

Understanding Entity Pages

This page aggregates everything SciDEX knows about CCL2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CCL2 is a protein involved in neurodegeneration research. Key relationships include: activates, regulates, therapeutic target. Associated with ALS, Als, Alzheimer. Connected to 253 entities in the SciDEX knowledge graph.

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graph TD
    CCL2["<b>CCL2</b>"]
    TNF["TNF"]
    CCL2 -->|"associated with"| TNF
    CXCL10["CXCL10"]
    CCL2 -->|"associated with"| CXCL10
    Inflammation{"Inflammation"}
    CCL2 -->|"activates"| Inflammation
    Multiple_Sclerosis{"Multiple Sclerosis"}
    CCL2 -->|"activates"| Multiple_Sclerosis
    ALS{"ALS"}
    CCL2 -->|"activates"| ALS
    Autoimmune{"Autoimmune"}
    CCL2 -->|"activates"| Autoimmune
    Neurodegeneration{"Neurodegeneration"}
    CCL2 -->|"activates"| Neurodegeneration
    Cancer{"Cancer"}
    CCL2 -->|"activates"| Cancer
    Cirrhosis{"Cirrhosis"}
    CCL2 -->|"activates"| Cirrhosis
    Carcinoma{"Carcinoma"}
    CCL2 -->|"activates"| Carcinoma
    Ms{"Ms"}
    CCL2 -->|"inhibits"| Ms
    CCL2 -->|"inhibits"| Autoimmune
    LACCER["LACCER"]
    LACCER -->|"regulates"| CCL2
    ASTROCYTE["ASTROCYTE"]
    ASTROCYTE -->|"associated with"| CCL2
    AKT["AKT"]
    AKT -->|"associated with"| CCL2
    B4GALT6["B4GALT6"]
    B4GALT6 -->|"activates"| CCL2
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"activates"| CCL2
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| CCL2
    NOTCH2["NOTCH2"]
    NOTCH2 -->|"activates"| CCL2
    DLL4["DLL4"]
    DLL4 -->|"activates"| CCL2
    PI3K["PI3K"]
    PI3K -->|"activates"| CCL2
    MTOR["MTOR"]
    MTOR -->|"activates"| CCL2
    AKT -->|"activates"| CCL2
    EGFR["EGFR"]
    EGFR -->|"activates"| CCL2
    style CCL2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0