Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CHKA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Hepatic Steatosis | suppresses | disease | 0.90 |
| EGF | activates | gene | 0.60 |
| EGFR | activates | gene | 0.60 |
| ERCC3 | activates | gene | 0.60 |
| PDK1 | activates | gene | 0.60 |
| PI3K | activates | gene | 0.60 |
| SMPD1 | activates | gene | 0.60 |
| PI3K-AKT-mTOR signaling | participates_in | pathway | 0.60 |
| neurons | expressed_in | cell_type | 0.55 |
| benchmark_ot_ad_answer_key:CHKA | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| DNMT1 | downregulates | protein | 0.90 |
| AKT | activates | gene | 0.60 |
| CEBPB | activates | gene | 0.60 |
| benchmark_ot_ad_answer_key:CHKA | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||