| Gene Symbol | HDAC11 |
| Aliases | Histone Deacetylase 11 |
| Chromosome | 3p25.2 |
| Protein Type | Gene |
| Function | encodes a protein of 347 amino acids with a molecular weight of approximately 39 kDa, making it the smallest mammalian HDAC. |
| Primary Expression | various brain regions including the cerebral cortex, hippocampus, cerebellum, and basal ganglia, with particular enrichment in neurons and, to a lesse |
| Subcellular Localization | </strong></td><td>Nucleus, Cytoplasm</td></tr> |
| Molecular Weight | 39 kDa |
| Amino Acids | 347 aa |
| Exons | 13 |
| Pathways | NF-κB |
| GeneCards | HDAC11 |
| Human Protein Atlas | HDAC11 |
| Rossmann-fold catalytic core | Central deacetylase activity |
| Zinc-binding motif | Required for catalytic function |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | HDAC3, HDAC5, HDAC7 |
| KG Connections | 62 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |