HDAC7

Understanding Entity Pages

This page aggregates everything SciDEX knows about HDAC7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

HDAC7 is a gene implicated in neurodegeneration research. Key relationships include: regulates, associated with, therapeutic target. Associated with ALS, Als, Alzheimer. Connected to 77 entities in the SciDEX knowledge graph.

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graph TD
    HDAC7["<b>HDAC7</b>"]
    myelination["myelination"]
    HDAC7 -->|"regulates"| myelination
    Tumor{"Tumor"}
    HDAC7 -->|"therapeutic target"| Tumor
    Als{"Als"}
    HDAC7 -->|"therapeutic target"| Als
    Neurodegeneration{"Neurodegeneration"}
    HDAC7 -->|"regulates"| Neurodegeneration
    Parkinson{"Parkinson"}
    HDAC7 -->|"regulates"| Parkinson
    Alzheimer{"Alzheimer"}
    HDAC7 -->|"regulates"| Alzheimer
    Neuroinflammation{"Neuroinflammation"}
    HDAC7 -->|"regulates"| Neuroinflammation
    Inflammation{"Inflammation"}
    HDAC7 -->|"regulates"| Inflammation
    Huntington{"Huntington"}
    HDAC7 -->|"regulates"| Huntington
    Ms{"Ms"}
    HDAC7 -->|"regulates"| Ms
    HDAC7 -->|"associated with"| Tumor
    ALS{"ALS"}
    HDAC7 -->|"associated with"| ALS
    JUN["JUN"]
    JUN -->|"associated with"| HDAC7
    JUN -->|"activates"| HDAC7
    MEF2D["MEF2D"]
    MEF2D -->|"regulates"| HDAC7
    PTEN["PTEN"]
    PTEN -->|"therapeutic target"| HDAC7
    PI3K["PI3K"]
    PI3K -->|"therapeutic target"| HDAC7
    GENES["GENES"]
    GENES -->|"therapeutic target"| HDAC7
    HDAC4["HDAC4"]
    HDAC4 -->|"associated with"| HDAC7
    AKT["AKT"]
    AKT -->|"therapeutic target"| HDAC7
    SIRT6["SIRT6"]
    SIRT6 -->|"regulates"| HDAC7
    HDAC11["HDAC11"]
    HDAC11 -->|"expressed in"| HDAC7
    HDAC2["HDAC2"]
    HDAC2 -->|"expressed in"| HDAC7
    SIRT7["SIRT7"]
    SIRT7 -->|"regulates"| HDAC7
    style HDAC7 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0