HDAC5

Understanding Entity Pages

This page aggregates everything SciDEX knows about HDAC5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

HDAC5 is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, inhibits. Associated with Als, Cancer, Carcinoma. Connected to 27 entities in the SciDEX knowledge graph.

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graph TD
    HDAC5["<b>HDAC5</b>"]
    Cancer{"Cancer"}
    HDAC5 -->|"activates"| Cancer
    Carcinoma{"Carcinoma"}
    HDAC5 -->|"activates"| Carcinoma
    Tumor{"Tumor"}
    HDAC5 -->|"activates"| Tumor
    STAT6["STAT6"]
    HDAC5 -->|"regulates"| STAT6
    HDAC5 -->|"activates"| STAT6
    Ferroptosis(["Ferroptosis"])
    HDAC5 -->|"activates"| Ferroptosis
    SLC7A11["SLC7A11"]
    HDAC5 -->|"activates"| SLC7A11
    TRIM28["TRIM28"]
    HDAC5 -->|"activates"| TRIM28
    FERROPTOSIS["FERROPTOSIS"]
    HDAC5 -->|"activates"| FERROPTOSIS
    CANCER["CANCER"]
    HDAC5 -->|"activates"| CANCER
    neurodegeneration["neurodegeneration"]
    HDAC5 -->|"implicated in"| neurodegeneration
    SIK1["SIK1"]
    SIK1 -->|"activates"| HDAC5
    SLC7A11 -->|"activates"| HDAC5
    CANCER -->|"activates"| HDAC5
    FERROPTOSIS -->|"activates"| HDAC5
    TRIM28 -->|"activates"| HDAC5
    STAT6 -->|"activates"| HDAC5
    AND["AND"]
    AND -->|"activates"| HDAC5
    TRIM28 -->|"inhibits"| HDAC5
    style HDAC5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0