| Gene Symbol | IDH3A |
| Full Name | Isocitrate Dehydrogenase 3 Alpha |
| Chromosome | 7q32.2 |
| Protein Type | Enzyme |
| Function | is a critical mitochondrial enzyme in the tricarboxylic acid (TCA) cycle that plays a pivotal role in cellular energy metabolism. |
| Subcellular Localization | Mitochondrial matrix |
| Molecular Weight | 46 kDa |
| Amino Acids | 413 aa |
| Pathways | Autophagy, Histone Modification |
| GeneCards | IDH3A |
| Human Protein Atlas | IDH3A |
| ADP | Activator, stimulates catalytic activity |
| ATP | Inhibitor, provides feedback on energy status |
| NADH | Inhibitor, reflects cellular redox state |
| Calcium | Activator, linking enzyme activity to neuronal activity |
| Associated Diseases | neurodegeneration |
| Interactions | TPM1, BNIP3, AND, MITOPHAGY, BCL-2, NAD |
| KG Connections | 23 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |