| Gene Symbol | IL34PROTEIN |
| Function | is a homodimeric cytokine that serves as the primary ligand for the colony-stimulating factor 1 receptor (CSF1R). |
| Primary Expression | Neurons, astrocytes |
| Molecular Weight | 20 kDa |
| Amino Acids | 188 aa |
| GeneCards | IL34PROTEIN |
| Human Protein Atlas | IL34PROTEIN |
| Feature | IL-34 |
| Primary structure | Different amino acid sequence |
| Receptor binding | Different epitope on CSF1R |
| Tissue expression | Neurons, astrocytes |
| Biological functions | Overlapping but distinct |
| Pathway | Primary Effect |
| PI3K/Akt | Cell survival, metabolism |
| MAPK/ERK | Cell proliferation |
| Associated Diseases | ALS, Alzheimer's disease, Parkinson's disease, neurodegeneration |
| Interactions | JAK2, STAT3 |
| KG Connections | 26 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |