protein 1,218 words KG: JAG1PROTEIN 2026-03-28
kind:proteinsection:proteinsstate:published
Contents

JAG1 Protein

🔬 Protein Info
Gene SymbolJAG1
Full NameJagged 1 (Notch Ligand)
Chromosome20p12.2
Functionis a critical member of the Notch ligand family that plays essential roles in cell fate determination, embryonic development, tissue homeostasis, and increasingly recognized functions in neurodegen...
Primary ExpressionCerebral cortex, Cochlea, Liver, Heart
Subcellular Localization</th><td>Plasma membrane</td></tr>
Molecular Weight134 kDa
Amino Acids218 aa
PathwaysNotch, NOTCH, Notch signaling
UniProt IDP78504
NCBI Gene ID1950
Ensembl IDENSG00000101384
OMIM184756
GeneCardsJAG1
Human Protein AtlasJAG1
Associated DiseasesALS, neurodegeneration
InteractionsNOTCH1, ULK1, Rb, NOTCH, RNA, APOPTOSIS
KG Connections202 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph